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Genomics|Features|Cancer Causes

Cancer Causes

Causes of Cancer: Role of Environment and Lifestyle - July 2, 2015

CDC Info

• Cancer prevention and control
• Human disease and bad luck: Acting on genetic & environmental factors to reduce cancer risk

Causality and chance in the development of cancer
Luzatto L et al, NEJMJuly 2, 2015

The implications of "random chance" in cancer genesis: Why stochastic can be a dirty word
Meisenberg BR, JAMA Oncology, May 7

Causes of Cancer
A Special Issue of the Annals of Epidemiology, March 2015

CDC blog post: Human disease and bad luck: Acting on genetic & environmental factors to reduce cancer risk

Musings on the theory that variation in cancer risk among tissues can be explained by the number of divisions of normal stem cells  [PDF 453.76 KB]
Tomasetti C and Vogelstein B

Cancer is not the result of bad luck, despite what headlines say, by David Hunter, the Boston Globe, Jan 15

Bad luck and cancer: A science reporter’s reflections on a controversial story, by Jennifer Couzin-Frankel, Science News, Jan 14

Most types of cancer not due to “bad luck” . IARC responds to scientific article claiming that environmental and lifestyle factors account for less than one third of cancers,  [PDF 41.96 Kb]Jan 13

Setting the record straight on cancer prevention: lifestyle trumps bad luck, Cancer News in Context, Jan 8

Causes of Cancer: Genes, Environment and Chance - January 8, 2015

Variation in cancer risk among tissues can be explained by the number of stem cell divisions. 
Cristian Tomasetti et al. Science, January 2, 2015

The simple math that explains why you may (or may not) get cancer. 
Jennifer Couzin-Frankel, Science, 1 January 2015

Bad luck of random mutations plays predominant role in cancer, study shows. --Statistical modeling links cancer risk with number of stem cell divisions, Johns Hopkins University, Jan 1, 2015

Who gets cancer? Bad luck plays a big role, AJC, Jan 1, 2015

Bad luck, bad journalism and cancer rates, The Guardian, Jan 2, 2015

What causes cancer? Find out what we know. The 13th Report on Carcinogens, from the National Institute for Environmental Health Sciences,  2014.

Epidemiology, epigenetics and the ‘Gloomy Prospect’: embracing randomness in population health research and practice. 
George Davey Smith, International Journal of Epidemiology, December 2014

CDC information on cancer prevention and control

Genes and environment: Cancer causes and risk factors, from the National Cancer Institute

Is cancer just bad luck? Part I. Known risk factors are poor predictors, by Ken Weiss , Mermaid Blog Post, Jan 5, 2015 

Is cancer just bad luck? Part II. It's a genetic, but usually unpredictable, disease, by Ken Weiss, Mermaid Blog Post, Jan 6, 2015

Cancer's random assault, by Denise Grady, New York Times, Jan 5, 2015

Bad luck, not genes or the environment, cause for many cancers, researchers find, PBS Newshour, Jan 2, 2015