Precision medicine UPDATE || Public Health Genomics Knowledge Base (v1.0) || July 7-14, 2016

Public Health Genomics Knowledge Base (v1.0)



July 7-14, 2016 


Last Updated: Jul 08, 2016

• Genetic testing can help deliver precision medicine to men with advanced prostate cancer
  Science News, July 7, 2016
• FDA advances Precision Medicine Initiative by issuing draft guidances on next generation sequencing-based tests
  FDA, July 6, 2016
• Lynch Syndrome Testing: A Missed Opportunity in the Era of Precision Medicine.
  Pasche Boris et al. JAMA 2016 Jul 316(1) 38-39
• NIH awards $55 million to build million-person precision medicine study
  NIH News, July 6, 2016
• Relevance of Health Literacy to Precision Medicine
  Division of Health and Medicine, National Academies Workshop in Brief, June 2016
• Medicine’s next step
  Barak Obama, Boston Globe, July 6, 2016
• Precision medicine in age-specific non-small-cell-lung-cancer patients: Integrating biomolecular results into clinical practice-A new approach to improve personalized translational research.
  Vavalà Tiziana, et al. Lung cancer (Amsterdam, Netherlands) 2016 5
• Codeine Pharmacogenetics as a Proof of Concept for Pediatric Precision Medicine.
  Hudak Mark L et al. Pediatrics 2016 Jun
• Genome variation in precision medicine
  Nature Genetics editorial, June 28, 2016
• Pharmacogenetics for Safe Codeine Use in Sickle Cell Disease.
  Gammal Roseann S et al. Pediatrics 2016 Jun
• Will precision medicine improve public health
  NCI online webinar debate by Drs S Galea and M. Khoury, June 27, 2016
• Towards Better Precision Medicine: PacBio Single-Molecule Long Reads Resolve the Interpretation of HIV Drug Resistant Mutation Profiles at Explicit Quasispecies (Haplotype) Level.
  Huang Da Wei et al. Journal of data mining in genomics & proteomics 2016 Jan (1)
• Systematic characterization and comparison of the CYP2C9 variability of the Orang Asli in Malaysia with 12 populations.
  Teh Lay Kek, et al. Drug metabolism and pharmacokinetics 2016 4
• FDA drug labeling: rich resources to facilitate precision medicine, drug safety, and regulatory science.
  Fang Hong et al. Drug discovery today 2016 Jun
• Biomarkers for the Clinical Use of PD-1/PD-L1 Inhibitors in Non–Small-Cell Lung Cancer: A Review
  JAMA Oncology, June 16, 2016

• CDC Information (17)
• CDC-Authored Pub (7)

• Human (218)
• Pathogen (0)

• Human (19)
• Pathogen (0)

• Human (27)
• Pathogen (1)

• Guidelines (3)
• Tier Table (0)
• Synthesis (3)

• Implementation (1)

Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB